# Which will decrease the affinity of oxygen to hemoglobin?

## Which will decrease the affinity of oxygen to hemoglobin?

In summary, the effect of low pH (and high PaCO2) is to decrease the affinity of haemoglobin for oxygen.

## Which factors would decrease the affinity of hemoglobin for oxygen quizlet?

PO2 is low, PCO2 is high, pH is low, and temperature is high. All of these factors decrease oxygens’s affinity for hemoglobin and therefore oxygen unloads from the hemoglobin and the hemoglobin saturation declines. 1. approximately 93% of carbon dioxide that enters the blood from the tissues diffuses into RBCs.