What is leading strand of DNA?
The leading strand is the strand of nascent DNA which is synthesized in the same direction as the growing replication fork. The synthesis of leading strand is continuous. The lagging strand, on the other hand, is the strand of new DNA whose direction is opposite to the direction of the growing replication fork.
What happens on the leading strand?
On the leading strand, DNA synthesis occurs continuously. On the lagging strand, DNA synthesis restarts many times as the helix unwinds, resulting in many short fragments called Okazaki fragments. DNA ligase joins the Okazaki fragments together into a single DNA molecule.
How do you identify the leading and lagging strands?
Leading strand refers to one of two strands of DNA found at the replication fork, being replicated continuously while lagging strand refers to the other strand found at the replication fork, replicating discontinuously in the to direction. Thus, this is the main difference between leading and lagging strand.