What are calcium phosphate crystals?

What are calcium phosphate crystals?

Basic calcium phosphate (BCP) crystals refer to a family of crystals including partially carbonate substituted hydroxyapatite, octacalcium phosphate, and tricalcium phosphate. These crystals have been found in and around joints and have been associated with several forms of arthritis and periarthritis.

What does calcium phosphate do in bones?

Calcium is necessary for many normal functions of the body, especially bone formation and maintenance. Calcium can also bind to other minerals (such as phosphate) and aid in their removal from the body. Calcium phosphate is used to prevent and to treat calcium deficiencies

What are bone crystals made of?

Bone mineral is formed by small, imperfect hydroxyapatite crystals, which contain carbonate, magnesium, sodium, and potassium.

What are the calcium crystals called that make up bone tissue?

Osteoid consists mostly of a fibrous protein called collagen, while the mineral complexes are made up of crystals of calcium and phosphate, known as hydroxyapatite, that are embedded in the osteoid. Bone also contains nutritive cells called osteocytes. However, the major metabolic activity in bone

What is the function of calcium phosphate crystals?

Calcium phosphates play important roles in cell adhesion and tissue formation by affecting the adsorption of extracellular matrix proteins on the surface [25, 26]. Their properties also influence bone regeneration by affecting newly formed bone minerals [27].

What is crystallized calcium phosphate?

Basic calcium phosphate (BCP) crystals refer to a family of crystals including partially carbonate substituted hydroxyapatite, octacalcium phosphate, and tricalcium phosphate. These crystals have been found in and around joints and have been associated with several forms of arthritis and periarthritis.

Where are calcium phosphate crystals found?

Calcium phosphate crystals are colorless and may appear as star-like or needle-like, though they may also form plates. They may show up alone or in clusters. They often appear in alkaline urine, though they can be found in normal urine. In rare cases, calcium phosphate crystals could by caused by hypoparathyroidism.

What causes calcium phosphate deposits?

Metastatic calcinosis can result from any medical condition associated with excess phosphorus (hyperphosphatemia) and calcium (hypercalcemia), including: kidney failure. sarcoidosisparaneoplastic hypercalcemia

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